the effect of policosanol on decrease of cholesterol, triglyceride and the other lipid metabolite levels in blood of wistar rats

background & aim: policosanol is a component from main alcohol groups with long-chain that extracted from cane sugar. in the present research, the effect of policosanol was investigated on decrease of lipid metabolite levels in blood of hypercholesterolemia rats. experimental: a number of 32 male wistar rats race with average weight of 250 g was divided into four groups including negative control group (n=8) that had normal diet, positive control and experimental groups i and ii (n=8) with high cholesterol diet of 2% cholestroled, and respectively they received placebo and policosanol with concentrations 0.25 and 0.5 mg/day. after four weeks, following the treatment of animals and bloodletting, the biochemical traits such as cholesterol biochemical, triglyceride, and ldl-c and hdl-c factors were measured. results & discussion: the results showed that in experimental group (i) there was a significant decrease (p